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Günter U Höglinger Selected Research

Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)

12/2021[Neuroprotective treatment of tauopathies].
10/2021Neuropathology of progressive supranuclear palsy after treatment with tilavonemab - Author's reply.
1/2021Clinical Features of Patients With Progressive Supranuclear Palsy in an US Insurance Claims Database.
1/2021Superiority of Formalin-Fixed Paraffin-Embedded Brain Tissue for in vitro Assessment of Progressive Supranuclear Palsy Tau Pathology With [ 18 F]PI-2620.
1/2021Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial.
1/2021In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies.
1/2021Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial.
1/2021iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression.
1/2021DescribePSP and ProPSP: German Multicenter Networks for Standardized Prospective Collection of Clinical Data, Imaging Data, and Biomaterials of Patients With Progressive Supranuclear Palsy.
11/2020Assessment of 18F-PI-2620 as a Biomarker in Progressive Supranuclear Palsy.
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Günter U Höglinger Research Topics

Disease

36Parkinson Disease (Parkinson's Disease)
07/2022 - 09/2003
25Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
12/2021 - 11/2005
19Tauopathies
12/2021 - 11/2005
16Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 11/2005
8Parkinsonian Disorders (Parkinsonism)
01/2021 - 01/2004
7Synucleinopathies
07/2022 - 07/2014
6Corticobasal Degeneration
12/2021 - 01/2018
6Disease Progression
01/2021 - 10/2013
5Alzheimer Disease (Alzheimer's Disease)
12/2021 - 12/2011
5Multiple System Atrophy
01/2019 - 01/2017
4Atrophy
01/2022 - 04/2014
3Movement Disorders (Movement Disorder)
08/2021 - 01/2020
3Cerebellar Ataxia (Dysmetria)
01/2019 - 02/2016
2Amyloidosis
10/2021 - 01/2021
2Glioma (Gliomas)
05/2021 - 01/2014
2Neuroinflammatory Diseases
01/2021 - 12/2020
2Chronic Obstructive Pulmonary Disease (COPD)
01/2020 - 01/2019
2Brain Diseases (Brain Disorder)
01/2020 - 12/2011
2Schizophrenia (Dementia Praecox)
12/2011 - 06/2011
1Confusion (Bewilderment)
01/2022
1Panic Disorder (Panic Attack)
01/2022
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
12/2021
1Pick Disease of the Brain (Pick's Disease)
12/2021
1Nervous System Heredodegenerative Disorders
07/2021
1Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease)
07/2021
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2021
1Tremor (Tremors)
01/2020
1Migraine Disorders (Migraine)
01/2020
1Myocardial Infarction
01/2020
1Nervous System Diseases (Neurological Disorders)
01/2020
1Essential Tremor (Essential Tremors)
01/2020
1Heart Diseases (Heart Disease)
01/2020
1Coronary Disease (Coronary Heart Disease)
01/2020
1Prodromal Symptoms
01/2019
1Gliosis
01/2019
1Lewy Body Disease (Lewy Body Dementia)
01/2018

Drug/Important Bio-Agent (IBA)

11Biomarkers (Surrogate Marker)IBA
10/2021 - 10/2013
8alpha-SynucleinIBA
07/2022 - 11/2005
8tau Proteins (tau Protein)IBA
12/2021 - 11/2005
8SynucleinsIBA
01/2021 - 02/2016
7Proteins (Proteins, Gene)FDA Link
10/2021 - 02/2016
6annonacinIBA
01/2017 - 01/2004
5Protein Isoforms (Isoforms)IBA
11/2021 - 12/2011
5Levodopa (L Dopa)FDA LinkGeneric
12/2017 - 10/2013
4Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
12/2021 - 11/2016
4tideglusibIBA
01/2017 - 04/2014
41- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
05/2015 - 01/2010
3LigandsIBA
01/2021 - 07/2017
3davunetideIBA
01/2017 - 07/2014
3Oxidopamine (6 Hydroxydopamine)IBA
05/2015 - 03/2008
2AntibodiesIBA
07/2022 - 01/2021
2Glucosylceramidase (Glucocerebrosidase)IBA
01/2022 - 09/2015
2Glucose (Dextrose)FDA LinkGeneric
10/2021 - 01/2021
2tilavonemabIBA
10/2021 - 01/2021
2MicroRNAs (MicroRNA)IBA
01/2021 - 01/2021
2Amyloid (Amyloid Fibrils)IBA
01/2021 - 01/2021
2PesticidesIBA
01/2020 - 11/2018
2Dopamine (Intropin)FDA LinkGeneric
07/2017 - 07/2004
2Phosphotransferases (Kinase)IBA
01/2017 - 08/2015
2NeurotoxinsIBA
01/2017 - 01/2008
2Dopamine Agonists (Dopamine Agonist)IBA
09/2015 - 10/2013
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
05/2015 - 12/2012
2Glycogen Synthase (Synthase I)IBA
04/2014 - 04/2014
2Neuregulin-1 (Neuregulin 1)IBA
12/2012 - 06/2011
2neuromelaninIBA
02/2011 - 01/2007
2AcetogeninsIBA
07/2007 - 01/2004
1Glucosylceramides (Glucocerebrosides)IBA
01/2022
1Cholinergic Agents (Cholinergics)IBA
01/2022
1GlycosphingolipidsIBA
01/2022
1venglustatIBA
01/2022
1Biological ProductsIBA
01/2022
1Amyloid beta-PeptidesIBA
12/2021
1Neuroprotective AgentsIBA
10/2021
1IronIBA
07/2021
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
01/2021
1gosuranemabIBA
01/2021
1Monoclonal AntibodiesIBA
01/2021
1Biocompatible Materials (Biomaterials)IBA
01/2021
1Formaldehyde (Formol)FDA Link
01/2021
1ParaffinIBA
01/2021
1Prescription DrugsIBA
01/2021
1Protein AggregatesIBA
01/2021
1Adrenergic Receptors (Adrenergic Receptor)IBA
01/2020
1Albuterol (Salbutamol)FDA LinkGeneric
01/2020
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
01/2020
1Propranolol (Inderal)FDA LinkGeneric
01/2020
1SmokeIBA
01/2020
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2019
1THK5351IBA
01/2019
1NicotineFDA Link
01/2019
1Monoamine Oxidase (MAO)IBA
01/2019
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
01/2019
1Mannitol (Osmitrol)FDA LinkGeneric
01/2019
1Cholinergic Antagonists (Anticholinergics)IBA
01/2019

Therapy/Procedure

12Therapeutics
05/2021 - 10/2007
2Activities of Daily Living (ADL)
02/2021 - 01/2020
2Drug Therapy (Chemotherapy)
01/2019 - 01/2019
1Aftercare (After-Treatment)
10/2021
1Immunotherapy
08/2021
1Polypharmacy
12/2017